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Impaired in vivo CD4+ T cell expansion and differentiation in aged mice is not solely due to T cell defects: decreased stimulation by aged dendritic cells

The TMD (1-4) topology that are connected by linker regions, the amino terminal end (NH 2 ) and the C-terminal domain (CTD) are shown

Researchers should look at baseline BMI, diabetes status, dose escalation, length of follow-up, plateau timing, regain after discontinuation, lean-mass preservation, and whether participants had obesity-related complications at entry